Phytochemical constituent, proximate analysis, antioxidant, antibacterial and wound healing properties of leaf extracts of Chromolaena odorata.

Phytochemical constituent, proximate analysis, antioxidant, antibacterial and wound healing properties of leaf extracts of Chromolaena odorata.

Author by Dr. Godswill Anyasor

Journal/Publisher: Annals Of Biological Research

Volume/Edition: 2

Language: English

Pages: 441 - 445

Abstract

This study investigated the phytochemical constituent, proximate analysis, antioxidant,
antibacterial and wound healing properties of aqueous and ethanolic leaf extracts of
Chromolaena odorata (L.). Results indicated the presence of saponins, phenols and tannins in
aqueous and ethanolic leaf extracts. Proximate analysis indicated that the dried leaf contained
ash (10.5%), crude fat (10.75%), fiber (14.9%), moisture (15%), crude protein (18.37%) and
carbohydrate (30.48%). However, aqueous extract had high antioxidant and lipid peroxide
inhibitory activity while ethanolic extract showed high phenolic and hydrogen peroxide
inhibitory activity at 50, 100 and 250 ?g/ml respectively. Furthermore, the antibacterial studies
showed that the ethanolic extract of C. odorata inhibited the growth of S. aureus, S. typhi and E.
coli at various degrees while S. aureus and S. typhi only were inhibited by the aqueous extracts.
However, aqueous extract (coagulation: 15.18 ± 0.023 min; clotting 0.26 ± 0.014 min) showed
significantly high (p<0> 0.696 min; Clotting 2.03 ± 0.035 min). The result of these studies indicates that leaf extracts of
C. odorata possess antioxidant, antibacterial and haemostatic activities which explain its
folkloric use in animal nutrition and human medicine.


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