Inhibition of rat liver mitochondrial membrane permeability transition and lipid peroxidation by seeds extracts of Myristica fragrans Houtt.

Inhibition of rat liver mitochondrial membrane permeability transition and lipid peroxidation by seeds extracts of Myristica fragrans Houtt.

Author by Dr. Godswill Anyasor

Journal/Publisher: Medicinal Plants

Volume/Edition: 9

Language: English

Pages: 1 - 5

Abstract

Myristica fragrans Houtt. seed commonly known as “nutmeg” is used in ethnomedical of practice as phytotherapy in the management of degenerative diseases. This study was designed to investigate the effects aqueous and dichloromethane extracts of M. fragrans seeds on calcium ion-induced rat liver mitochondrial membrane permeability transition (MMPT) and lipid peroxidation. Results indicated that 50, 150 and 300 ?g/mL aqueous extract of M. fragrans seeds had a significantly (P<0>


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