Background: Offspring of patients with bipolar disorder have genetic and environmental predisposition to psychiatric disorders. The impact of these vulnerabilities on their psycho-social functioning is not completely known.
Aim: To assess psycho-social functioning in offspring of parents with bipolar disorder (OBP), as compared with a matched control of children whose parents have no psychiatric disorder (OCP).
Method: OBP (n=100) at the Federal Neuro-Psychiatric Hospital, Yaba and OCP (n=100) were assessed with a socio-demographic questionnaire, Schedule for Affective disorders and Schizophrenia for school aged children (K-SADS-PL) and Children’s Global Assessment Scale (CGAS).
Results: OBP were more likely to be functionally impaired than OCP (OR=2.88, 95% CI=1.217-4.275, p<0 p=0.002), p=0.028) p=0.013).>
Conclusion: Parental psychopathology and other psychosocial factors negatively impacts on the functioning of OBP. Interventions targeted towards these factors may improve functioning in these children.