Urinary aflatoxin exposure monitoring in rural and semi-urban populations in Ogun state, Nigeria

Urinary aflatoxin exposure monitoring in rural and semi-urban populations in Ogun state, Nigeria

Author by Prof. Chibundu Ezekiel

Journal/Publisher: Food Additives & Contaminants: Part A

Volume/Edition: 35

Language: English

Pages: 1565 - 1572

Abstract

Aflatoxins are a major class of fungal toxins that have food safety importance due to their
economic and health impacts. This pilot aflatoxin exposure biomonitoring study on 84 individuals
was conducted in a rural (Ilumafon) and a semi-urban community (Ilishan Remo) of Ogun state,
Nigeria, to compare aflatoxin exposures among the two population cohorts. First morning urine
samples were obtained from the participants, and the urinary aflatoxin M1 (AFM1) levels were
measured by a quantitative Helica Biosystems Inc. ELISA kit assay. About 99% (83 out of 84) of the
urine samples had detectable AFM1 levels in the range of 0.06 to 0.51 ng mL?1 (median: 0.27
ng mL?1). The mean urinary AFM1 levels were significantly (p = 0.001) higher in the semi-urban
population (0.31 ± 0.09 ng mL?1) compared to the rural population (0.24 ± 0.07 ng mL?1). There
were, however, no significant differences in mean urinary AFM1 levels of males and females, and
among children, adolescents and adults. This study indicates high aflatoxin exposure to the
extent of public health concerns in the studied populations. Thus, more efforts are required for
aflatoxin exposure monitoring and control in high-risk regions.

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