The study examines the combined and relative effects of Economic, Nature and Society on Premarital sex. It made use of simple random technique in selecting 250 youths within Ikenne local governmentin Ogun State, Nigerian. The age range of the respondents was between 15 to 35 years with the mean age of 24.5 and standard deviation of 3.291. The ex-post-facto research design was employed. A 35 item; Youth Attitude towards Sexual Practices (YATSP) developed by the Researcher was used to generate data for the study. All the hypotheses data were tested at 0.05 level of significance. Data analysis involved the use of multiple regressions (backward), ANOVAand Pearson product moment Correlation. The result indicated in model 3, that the predictors’ variables accounted for 56.4% percent of the variation in premarital sexual activities.Each ofthe independent variables contributes significantly to the Premarital Sexual activitiesand a perfect positive correlation existed between Premarital Sexual activities and the three independent variables.Suggestions were made based on the outcome.