Job enrichment and employee commitment for ages have been a difficult issue for human resource managers of organizations worldwide. Numerous researches have been carried out over the past years with the aim of resolving this problem. However, little research has been conducted to determine the effectiveness of job enrichment in private universities in Nigeria. This study therefore, evaluated the effects of job enrichment on employee commitment of non-academic staff in selected private Universities in South-West Nigeria. This study employed a cross-sectional survey design. The population of the study was 2462 non-academic staff distributed among the seven (7) approved private universities that had existed for six years in South-West Nigeria. A sample of 740 respondents was selected using multi-stage sampling technique. 618 filled questionnaires were returned but 547 was found useable. The simple regression model was used to analyse the data collected. The findings revealed that job enrichment had a statistically significant positive effect on employee commitment of non-academic staff in the selected private universities in SouthWest Nigeria. This findings shows that non-academic staff in the sample Universities are committed to their work as the result of the practice of job enrichment. However, the study recommended that managers and human resources managers of the surveyed Universities and other private and public universities and other organizations should pay more attention to job enrichment practices as to keep employee committed all the time.