Therapeutic Effect of White Cabbage (Brassica oleracea) Aqueous

Therapeutic Effect of White Cabbage (Brassica oleracea) Aqueous

Author by Dr. Bolade Adeoye

Journal/Publisher: Journal Of Applied Sciences

Volume/Edition: 19

Language: English

Pages: 413 - 420


Background and objective: Some plant materials have been found to possess hypoglycemic property which could ameliorate hyperglycemic condition. Thus, this study aimed at determining the effect of cabbage on hyperglycemia. Materials and Methods: Extracts from fresh and dried cabbage, and thirty male albino rats grouped into six were used for the study. The groups were the positive control (fed regular diet), negative control (fed high sucrose feed) and treatment (high sucrose feed and extract for two weeks) groups. Each of the treatment groups received 50 mg or 100 mg per kg bodyweight of either of fresh and dried cabbage extracts.  The fasting blood sugar (FBS) was determined at baseline and at two weeks interval. The experiment lasted six weeks when the serum insulin, oral glucose tolerance test and liver oxidative stress were determined. Data were subjected to Graph pad prism 5 and the blood glucose was analysed using analysis of variance (ANOVA) at P<0>Results: There was a reduction in the blood sugar and resistance to insulin by the extracts.  The control negative had the highest fasting blood sugar (62 mg/dl) and the result of oral glucose tolerance also showed higher peak at 60 min. There was a reduction in the MDA (0.54±0.08- 0.79±0.05) accompanied by significant reduction in the SOD (0.52±0.04 - 0.57±0.04) and CAT (1.85±0.65- 15.75±1.69) of the test groups. Conclusion: Potential of cabbage to control blood sugar and ameliorate oxidative stress of the liver was demonstrated in this study.

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