Purpose: This study was conducted to assess the prevalence of refractive error among secondary school students, as well as their intention to use prescription glasses regularly. Methods: This was a cross-sectional school-based study with a qualitative component. A total of 359 secondary students aged 11-22years, were selected by multistage sampling method from seven schools in Ogijo community, Ogun state, Nigeria. Of the 359 students, 353(98.3%) were examined. The examination included Visual acuity measurement, ocular motility tests, retinoscopy & autorefraction under cycloplegia, and anterior & posterior segment examination. The data collected were analysed using the statistical package for social sciences (SPSS). Results: The prevalence of refractive error was 11.6%, and of the 41 participants who had refractive error, 65.9% were females while 34.1% were males. Myopia was at 5.1%, while hyperopia and astigmatism were 3.7% and 2.8% respectively. Participants had adequate information (`x =16.08 SD±2.29) regarding refractive error and the use of prescription glasses, but revealed a lack of motivation towards prescription glasses use (`x15.8 SD±4.2). Overall, participants expressed good intention to regular prescription glasses use (`x =12.89 SD±3.8). Conclusion: Refractive error among secondary students of Ogijo community, Ogun state, Nigeria is relatively high. The students expressed good intention to use prescription glasses regularly if given, but on certain conditions. A comprehensive school health program that incorporates school eye health promotion should be practiced effectively to address the misconceptions regarding the use of prescription glasses among the teachers, parents and students.