Background: Unintended pregnancies and unsafe abortion is a global health issue and can be prevented through the use of contraceptive were sexual abstinence is impracticable. Unsafe sexual practices have drastic consequences on sexual and reproductive health and contributes immensely to maternal mortality. Objective: The objective of this study was to determine how level of knowledge and behavioural skill predicts contraceptive-use among female undergraduates in a selected university in Ogun state, Nigeria. Methodology: This was a descriptive cross-sectional study conducted among 241 female undergraduates using a validated interviewer administered questionnaire. Descriptive statistics, Pearson correlation and Logistic regression analysis was used to determine which construct best predicts contraceptive-use using SPSS version 24.0. Results: Study revealed level of knowledge of respondents was 6.56 ± 1.85 with a prevalence score of 54.6%, mean score for behavioural skill was 6.50 ± 4.44 with a prevalence score of 27.1% and mean score for contraceptive-use was 2.68 ± 1.92 with a prevalence score of 38.28%. Behavioural skill was significantly associated with contraceptive-use (R= 0.400; R 2=0.16; p=0.00) hence a better predictor of contraceptive-use. Conclusion: Findings from this study shows there is need for sensitization and empowerment of women with the aim of increasing their behavioural skill as knowledge alone is not sufficient in increasing the use of contraceptives where sexual abstinence is impracticable.