The study employed the Ex Post Facto research design. The population consisted of 169 Quoted companies in Nigeria. The sample size consisted of 10 manufacturing companies in Nigeria. Data from the research were obtained from financial statements and annual reports of the sampled companies. Data were analyzed through Descriptive and Inferential statistics. Findings revealed that accounting information have a significant effect on the prediction of investor’s return of listed firms in Nigeria. The study concluded that accounting information have effect on the prediction of investor’s return of listed firms in Nigeria. The study recommended that Management of listed firms in Nigeria should maintain stability and consistency in their earnings, while avoiding earnings management as much as possible. This is by employing uniform accounting policy in accordance with the relevant accounting standards for the preparation of financial accounting information. Management of listed firms in Nigeria should create more innovative ideas and inventions that are substantial enough to project the earnings of the organizations to acceptable level.