Multi-drug resistance in Salmonella species is becoming a great problem in healthcare institutions resulting in high mortality rate due to its infections. Hence, the purpose of this study was to evaluate the antibiogram of Salmonella species obtained from various environmental samples in Ogun state. Samples (150) comprising faecal droppings of cow, goat, bird and pig as well as pond wastewater were obtained and Salmonella species were isolated using Xylose Lysine Deoxycholate agar and identified using analytical profile index. The susceptibility of the species was evaluated and interpreted according to CLSI guidelines. Fifty (50) species of Salmonella species were obtained and all (100%) were resistant to ceftazidime, gentamicin, while 92%, 90%, 48%, 46%, and 44% were resistant to amoxicillin/clavulanate, cefuroxime, cefixime, ciprofloxacin, ofloxacin, and nitrofurantoin respectively. Multi-drug resistance was noted in Salmonella species to at least three antibiotic classes. The results revealed high prevalence and multi-drug resistant Salmonella species in our environment. Hence measures should be implemented urgently to curb further spread of multidrug resistant Salmonella species in our environment.