THE ANTIBIOTIC RESISTANCE PROFILE OF STAPHYLOCOCCUS ISOLATES IN OUTPATIENT INFERTILE SUBJECTS IN ESAN, NIGERIA

THE ANTIBIOTIC RESISTANCE PROFILE OF STAPHYLOCOCCUS ISOLATES IN OUTPATIENT INFERTILE SUBJECTS IN ESAN, NIGERIA

Author by Dr. Eghosa Morgan

Journal/Publisher: World Journal Of Pharmacy And Pharmaceutical Sciences

Volume/Edition: 7

Language: English

Pages: 115 - 127

Abstract

This study investigates the antibiogram pattern of staphylococcus species isolates from infertile subjects with urinary tract infection in Esan-Nigeria, considering the variation in antibiotics susceptibility pattern based on location, gender and season. It is our assertion that comorbidity with other health issues can also influences antibiotics susceptibility and resistivity activities. A retrospective study was carried out among individuals with fertility problems and positive for urinary tract infections from three health facilities within the period of January 2013 to December 2013. Collected samples; semen and high vaginal swab were screened for UTI and antibiotic susceptibility of isolated Staphylococcus species pathogens and tested against 21 antibiotics. 220 samples were analyzed and made up of 139 semen and 81 high vaginal swab samples. In the semen samples were isolated 75.54% Staphylococcus aureus, 23.02% Staphylococcus saprophyticus and 1.44% Staphylococcus epidermidis and isolates in the high vaginal swabs were 76.54% of S. aureus and 23.46% of S. saprophyticus. Cefuroxime (21.10%) and Norfloxacin (40.63%) were the most sensitive against S. aureus and S. saprophyticus in the semen samples. On the other hand, Cephalexin (25.81%) and Streptomycin (26.32%) were the most sensitive against S. aureus and S. saprophyticus in the HVS samples. Ampicillin, Cloxacilin, Augmentin, Ampiclox, Cotrimoxazole, Chloramphenicol, Lincocin, Erythromycin, Azithromycin, Tetracycline, Cefuroxime, Norfloxacin, and Ciprofloxacin and Cephalexin were the most resistant against organism in semen and HVS isolates


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