Abstract
The leaf pulp of Carpobrotus edulis has antibacterial, antifungal, and tissue regeneration abilities. Chromium is a ubiquitous contaminant that has raised a major concern due to its level of toxicity. This study investigated the therapeutic role of leaf pulp of Carpobrotus edulis on chromium VI-induced toxicity in male Wistar rats. Thirty rats were divided into five groups of six rats, each comprising group 1 (control group), given 0.5 mL of de-ionized water. Group 2 was pre-treated with 0.5 mL of the leaf pulp for seven consecutive days, and afterward, 5 mg/kg potassium dichromate (K2Cr2O7) was administered for another seven days. Group 3 was given 5 mg/kg K2Cr2O7 for seven days and 0.5 mL of the leaf pulp after that. Group 4 was given only 5 mg/kg K2Cr2O7 for 7 days, and group 5 was treated with 0.5 mL of the plant leaf pulp for 14 days. The rats were sacrificed under mild diethyl ether anesthesia twenty-four hours after the last treatment. The blood, liver, and kidney were collected and used for hematological, biochemical, and morphological analyses. Significant increases (p<0>