Leaf Pulp of Carpobrotus deliciousus Attenuate Sodium Arsenate Induced Toxicity

Leaf Pulp of Carpobrotus deliciousus Attenuate Sodium Arsenate Induced Toxicity

Author by Dr. Abolanle Kayode

Journal/Publisher: Letters In Applied Nanobioscience

Volume/Edition: 12

Language: English

Pages: 1 - 13

Abstract

Abstract: Carpobrotus deliciousus (CD) is reported to have numerous health benefits. This study determined the influence of the oral and repeated administration of leaf pulp of C. deliciousus (LPCD) on sodium arsenate (SA) (Na3AsO4) induced toxicity in Wistar rats. Thirty male Wistar rats were distributed into five groups of six rats each. Group 1 was given 5 mg/kg body weight (b.w) of SA for 7 days; group 2 was administered 0.5 mL of LPCD for 14 days. Group 3 received 5 mg/kg b.w of SA for 7 days followed by 0.5 mL LPCD for another 7 days, while group 4 was treated with 0.5 mL LPCD for 7 days followed by 5 mg/kg b.w of SA for another 7 days. Group 5 served as the control and received deionized water. After the last treatment, the blood, kidneys, and liver were collected for biochemical analysis. The alkaline phosphatase (ALP), AST, and GPT levels were all significantly (p < 0>

Keywords: sodium arsenate; toxicity; Carpobrotus deliciousus; leaf pulp; organ damage


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