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Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger

Authors: Mensah-Agyei Grace

Publication Type: Journal article

Journal: Journal Of Infection And Public Health

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Abstract

Background: The effective management of maternal and infant malaria requires rational and prompt diagnosis. This study aims to determine the diagnostic efficiency of malaria RDT in infants and pregnant women. Methods: The study was conducted on infants (n = 200), pregnant women (n = 80) and non-pregnant women (n = 100) who were recruited from two hospitals in Lagos, Nigeria. Plasmodium falciparum infections were assessed in the febrile subjects by microscopic examinations of blood smears and by RDT. Results: The lowest (44.3%) and the highest (83.3%) sensitivity (SS) values were recorded in the infants and pregnant women, respectively. Other diagnostic parameters, including the specificity (SP, 97.5%), positive predictive value (PPV, 92.1%) and negative predictive value (NPV, 72.8%), in the infants were greater than the values recorded in non-pregnant (SP = 77.5%, PPV = 83.9%, NPV = 70.5%) and pregnant women populations (SP = 65.6%, PPV = 78.4%, NPV = 72.4%). The diagnostic efficiency of malaria RDT exhibited higher sensitivity in women in early gestational stages (1st trimester = 78.6% and 2nd trimester = 88.0%) compared with those in the 3rd trimester (71.4%). The sensitivity of malaria RDT (100.0%) was significantly higher in the multigravid women than in the primigravida (78.6%) and secundigravida women (77.8%, P < 0>

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Mensah-Agyei,G. . (2016). Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger, 9 (), 471-471.

Mensah-Agyei,G. . "Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger" 9, no (), (2016): 471-471.

Mensah-Agyei,G. and . (2016). Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger, 9 (), pp471-471.

Mensah-AgyeiG, . Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger. 2016, 9 ():471-471.

Mensah-Agyei,Grace , . "Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger", 9 . (2016) : 471-471.

M.Grace , "Reliability of rapid diagnostic tests in diagnosing pregnancy and infant-associated malaria in Niger" vol.9, no., pp. 471-471, 2016.

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