Abstract

Cement dust emission into the environment from various points is a major pollution problem in cement factory, with cement dust constituent differing at each point of production, therefore, suggesting toxicity implications at each points of production might differ. The present study determines the levels of serum immunoglobulin classes (IgA, IgG, IgM, IgG) and total bilirubin, alkaline phosphatase(ALP), aspatase aminotransferase (AST), alanine aminotransferase(ALT), total protein, albumin, creatinine, uric acid and gamma glutamyl transferase in forty five(45) cement factory workers working in different sections of the factory ( Crushing (13) , Milling(19) and Packing sections (13) ). Immunodiffussion method was used to determine serum IgA, IgG, IgM while ELISA method was used to determine serum IgE. Alkaline phosphatase(ALP), alanine amino transferase(ALT), aspatase aminotransferse, total bilirubin, albumin, creatinine and uric acid were determined using Hitachi 902 auto analyser while gamma glutamyl transferase (GGT) was determined using colorimetric method. The levels of IgM, IgA and IgE were not statistically different among the groups (p>0.05) while IgG was significantly higher in workers working in the packing section of the factory (p<0.05) when compared with the other two sections. Also, total bilirubin, albumin, AST, ALT, ALP were significantly higher (p<0.05) in workers at the crushing section, uric acid is also significantly higher in workers at the milling section (p<0.05) but creatinine and GGT were not significantly different (p>0.05) though with a higher mean levels when compared with the general population. This study demonstrated that workers in cement factory working in different sections are susceptible to various diseases specific to their work area. [Effects Of Different Cement Factory Sections Products On Immunoglobulin Levels And Some Biochemical Parameters In Nigeria Cement Factory Workers.