Serum trace metals in diagnosis and prognosis of post-menopausal breast cancer in a tertiary health
Authors:
NWOBI Nnenna
Publication Type: Journal article
Journal: Archives Of Applied Science Research
ISSN Number:
0
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Abstract
The levels of trace elements in the serum of postmenopausal breast cancer patients were determined and correlated with Tumour Parameters Index (TPI) ,developed for this study, in order to study their contributions in breast cancer diagnosis and evaluate their prognostic value. Serum zinc, selenium, lead, iron, copper, cadmium were estimated using atomic absorption spectrophotometry in 63 newly diagnosed postmenopausal breast cancer patients and compared with 63 apparently healthy controls. TPI was derived by a composite of six parameters that are conceptually relevant to tumour characteristics on a maximum 15-point scale and normality was assured. The results showed significantly higher mean levels of Pb(ug/L) (71.02±0.01)(p<0 xss=removed>