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A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria

Authors: Adediji Isaac , IHONGBE John , & Olasebikan

Publication Type: Journal article

Journal: International Journal Of Biomedical And Advance Research

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Abstract

Introduction: Helicobacter pylori infection is one of the commonest bacterial infections in human world-wide. H.pylori is a significant cause of a number of intra-digestive and extra-digestive disorders with increased prevalence in the developing countries.
Objectives: This study investigated the relationship between platelet count and peptic ulcer and also compared the results of the test subjects with the controls.
Methodology: Sixty subjects (age: 27.5±3.2) were enrolled for the study which included forty newly diagnosed peptic ulcer patients from the Medical Outpatient Clinic of a tertiary health institution in Ogun State, Nigeria and twenty age-matched, apparently healthy individuals from the same geographical location were selected as controls. Platelet count analysis was done with BC-5300 Auto Haematology analyzer and the detection of serum H.pylori antibodies was done using diaspot rapid chromatographic immunoassay method. Data obtained were statistically analysed using ANOVA, Post-Hoc and Pearson’s correlation. P<0> Results: The platelet count was significantly low in H.pylori infected peptic ulcer subjects when compared with both H.pylori negative peptic ulcer subjects and controls (p<0> Conclusion: The study concluded that, not all cases of peptic ulcer are associated with thrombocytopenia however, thrombocytopenia in peptic ulcer subjects, is solely associated with H.pylori infection.

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Adediji,I. IHONGBE,J. ,O. . (0000). A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria, 6 (), 522-522.

Adediji,I. IHONGBE,J. ,O. . "A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria" 6, no (), (0000): 522-522.

Adediji,I. and IHONGBE,J. and ,O. and . (0000). A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria, 6 (), pp522-522.

AdedijiI, IHONGBEJ, O, . A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria. 0000, 6 ():522-522.

Adediji,Isaac , IHONGBE,John , and ,Olasebikan . "A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria", 6 . (0000) : 522-522.

A.Isaac I.John & .Olasebikan , "A correlative study of peptic ulcer and thrombocytopenia in Remo land of Ogun State, Nigeria" vol.6, no., pp. 522-522, 0000.

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