This research was undertaken to determine the effect of fowl cholera on laying hen productivity. The possible causes of the problem were identified and the measures to control future occurrence were also suggested. The economic implication was discussed. Results revealed a significant difference (p?0.5) between the 25th week and 28th weel as a declining trend in egg production was observed. After treatment, there was a dramatic increase in egg production on the 3oth week, with progressive increase in subsequent weeks. The mortality observed from the 26th to 28th weeks began to decline from the 29th week.