Babcock University Research Portal

Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery

Authors: ADETAYO Adekunle , ADETAYO Modupe , OYEDELE Titus , Akeju , Adepoju , Jaiyesimi , Sotunsa , Bhutta Za

Publication Type: Journal article

Journal: Babcock University Medical Journal

ISSN Number:

Downloads

Views

Abstract

Background/Aim: The adverse effects of mandibular third molar surgery on the quality of life show a three-fold increase in patients who experience pain, swelling and trismus. It is therefore imperative that these postoperative sequelae are well controlled in patients who undergo third molar surgery. The aim of this study was to compare the effects of administration of both preoperative and postoperative dexamethasone with that of only preoperative dexamethasone, and with that of a no dexamethasone (control) on reduction of pain, trismus and swelling following lower impacted 3rd molar surgery.

Methods: The study was a prospective randomized controlled double blinded study carried out the dental clinic of Babcock University Teaching Hospital on 84 subjects that were divided into 3 groups, A, B and C. Group A had both preoperative and postoperative dexamethasone, while group B had only preoperative dexamethasone and group C was no dexamethasone group. Preoperative and postoperative facial dimensions were taken, and mean differential facial swelling and mouth opening was calculated. Pain scores measured with Visual Analogue Scale were also calculated post-operatively at day 1, 3 and 7. Differential mean swelling and mouth opening, and pain scores were compared within the three groups.

Results: The pattern of postoperative swelling, pain and trismus showed a general decrease from day 1 to 7, with group A showing the highest rate of decrease. On postoperative day 1, there was a difference between the swelling of groups A and C (p = 0.01) and groups B and C (p = 0.02) and also between the pain scores of group A and group C (p = 0.01). On postoperative day 3, there was only a difference between the swelling of groups A and C (p = 0.02), but not in pain and trismus and no difference was seen in all the measured variables on postoperative day 7.

Conclusion: Administration of a combination of both preoperative and postoperative dexamethasone to reduce the postoperative inflammatory sequelae that follows lower third molar surgery gave better results than administration of only a single preoperative dose.

Access to Documents

External Link
Download
Digital Object Identifier

Keywords

ADETAYO,A. ADETAYO,M. OYEDELE,T. Akeju,D. Adepoju,A. Jaiyesimi,E. Sotunsa,J. Bhutta,Z. . (2017). Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery, 2 (), 8-8.

ADETAYO,A. ADETAYO,M. OYEDELE,T. Akeju,D. Adepoju,A. Jaiyesimi,E. Sotunsa,J. Bhutta,Z. . "Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery" 2, no (), (2017): 8-8.

ADETAYO,A. and ADETAYO,M. and OYEDELE,T. and Akeju,D. and Adepoju,A. and Jaiyesimi,E. and Sotunsa,J. and Bhutta,Z. and . (2017). Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery, 2 (), pp8-8.

ADETAYOA, ADETAYOM, OYEDELET, AkejuD, AdepojuA, JaiyesimiE, SotunsaJ, BhuttaZ, . Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery. 2017, 2 ():8-8.

ADETAYO,Adekunle , ADETAYO,Modupe , OYEDELE,Titus , Akeju,Do , Adepoju,A , Jaiyesimi,E , Sotunsa,J , and Bhutta,Za . "Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery", 2 . (2017) : 8-8.

A.Adekunle A.Modupe O.Titus A.Do A.A J.E S.J & B.Za , "Comparison of the effect of two-dose and one-dose dexamethasone on post inflammatory complications in third molar surgery" vol.2, no., pp. 8-8, 2017.

Access to Documents

Keywords

About Us

Admissions

Contact Us

Policies

ALUMNI

STUDENT POPULATION