Babcock University Research Portal

Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens

Authors: ENITAN Samson , Paul , ADEJUMO Esther , Richard , Omolara Owolabi

Publication Type: Journal article

Journal: Open Science Journal Of Pharmacy And Pharmacology

ISSN Number:

Downloads

Views

Abstract

This present study investigated the antimicrobial potential of the leaf and stem extracts of Gongronema latifolium against some
selected wound-associated pathogens: Pseudomonas aeruginosa, Escherichia coli, Proteus mirabilis, Klebsiella pneumonae
and Candida albican using the punch-hole agar diffusion method. The outcome of the study show that neither the aqueous nor
the methanolic leaf and stem extracts of Gongronema latifolium showed any inhibitory activity against the bacterial and fungal
isolates at all the concentrations (200, 150, 100 50 and 25 mg/mL) tested either singly or combined; whereas the positive
control was effective against all of them; with zones diameter of inhibition ranging between 18-24 mm (Pseudomonas
aeruginosa), 17-23 mm (Escherichia coli), 15-23 mm (Proteus mirabilis), 18-22 mm (Staphylococcus auerus) and 17-24 mm
(C. albicans). On the other hand, as expected, the negative control (distilled water) did not show any zone of inhibition. The
antibacterial activity of the positive control was statistically significant at P value <0> and negative control. Although the antimicrobial potential of extracts of G. latifolium have been previously demonstrated
against various clinical isolates, the findings in this current study did not support claims made by different researchers in
previously studies. All the test isolates were found to be resistant to the extracts. Lack of inhibitory activity by extracts of G.
latifolium growing in Irolu, Ikenne Local Government Area of Ogun state in this present study is plausible and would require
further investigation. Due to differences in topographical factors of various geographical locations, nutrient concentrations of
the soil, chemical composition, age and time of harvest of the plant, extraction method as well as method used for
antimicrobial study; it is therefore important that scientific protocols be clearly identified, adequately followed and reported.

Access to Documents

External Link
Download
Digital Object Identifier

Keywords

ENITAN,S. Paul,O. ADEJUMO,E. Richard,A. Omolara,O. . (2017). Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens, 5 (), 34-34.

ENITAN,S. Paul,O. ADEJUMO,E. Richard,A. Omolara,O. . "Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens" 5, no (), (2017): 34-34.

ENITAN,S. and Paul,O. and ADEJUMO,E. and Richard,A. and Omolara,O. and . (2017). Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens, 5 (), pp34-34.

ENITANS, PaulO, ADEJUMOE, RichardA, OmolaraO, . Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens. 2017, 5 ():34-34.

ENITAN,Samson , Paul,Omodiale , ADEJUMO,Esther , Richard,Akele , and Omolara,Owolabi . "Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens", 5 . (2017) : 34-34.

E.Samson P.Omodiale A.Esther R.Akele & O.Owolabi , "Evaluation of the Antimicrobial Potential of Gongronema latifolium Extracts on Some Wound-Associated Pathogens" vol.5, no., pp. 34-34, 2017.

Access to Documents

Keywords

About Us

Admissions

Contact Us

Policies

ALUMNI

STUDENT POPULATION