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A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers

Authors: Oyetunde , Ezekiel Chibundu , AYENI Kolawole , Nabofa Enivwenaye , Ifeoluwa , OYEDELE Oluwawapelumi , ADEFALUJO Adekunle , NWOZICHI Chinomso , Adeyemi Dada

Publication Type: Journal article

Journal: African Journal Of Urology

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Abstract

Abstract Objective: To correlate the levels of bladder tumour antigen (BTA) with aflatoxin M1 (AFM) in a human population in Nigeria. 23 24 Subjects and methods: A pilot, observational study was conducted with 22 human subjects randomly recruited from a Nigerian rural community. Serum and first morning urine of participants were analysed for human BTA and AFM1, respectively, using quantitative ELISA assays. 25 26 27 Results: All the subjects were positive to AFM1 (mean = 0.235 ± 0.072 ng/mL) while 19 were positive to BTA (mean = 2.340 ± 1.741 ng/mL). A negative relationship occurred between human BTA and AFM level (r = ?0.239; P = 0.285). Human BTA (2.86 ± 2.43 ng/mL; P = 0.306) and AFM1 (0.258 ± 0.065 ng/mL; P = 0.643) were higher in subjects 1–20 years. The two biomarkers were not also associated with sexes of the participants (P>0.05), although they were higher in the female subjects.

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Oyetunde,O. Ezekiel,C. AYENI,K. Nabofa,E. Ifeoluwa,O. OYEDELE,O. ADEFALUJO,A. NWOZICHI,C. Adeyemi,D. . (2018). A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers, 24 (), 153-153.

Oyetunde,O. Ezekiel,C. AYENI,K. Nabofa,E. Ifeoluwa,O. OYEDELE,O. ADEFALUJO,A. NWOZICHI,C. Adeyemi,D. . "A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers" 24, no (), (2018): 153-153.

Oyetunde,O. and Ezekiel,C. and AYENI,K. and Nabofa,E. and Ifeoluwa,O. and OYEDELE,O. and ADEFALUJO,A. and NWOZICHI,C. and Adeyemi,D. and . (2018). A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers, 24 (), pp153-153.

OyetundeO, EzekielC, AYENIK, NabofaE, IfeoluwaO, OYEDELEO, ADEFALUJOA, NWOZICHIC, AdeyemiD, . A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers. 2018, 24 ():153-153.

Oyetunde,Oyeyemi , Ezekiel,Chibundu , AYENI,Kolawole , Nabofa,Enivwenaye , Ifeoluwa,Oyeyemi , OYEDELE,Oluwawapelumi , ADEFALUJO,Adekunle , NWOZICHI,Chinomso , and Adeyemi,Dada . "A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers", 24 . (2018) : 153-153.

O.Oyeyemi E.Chibundu A.Kolawole N.Enivwenaye I.Oyeyemi O.Oluwawapelumi A.Adekunle N.Chinomso & A.Dada , "A pilot biomonitoring study of bladder tumor antigen (BTA) in aflatoxin exposed Nigerian villagers" vol.24, no., pp. 153-153, 2018.

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