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Moringa leaf extract potential in the incidence of allergy in experimental rats

Authors: ADEYEYE Joshua

Publication Type: Journal article

Journal: Nigerian Journal Of Animal Production

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Abstract

The incidence of food allergyoutbreak worldwide is becoming a public health concern. Food
allergy is growing at an epidemic proportion affecting all age groups of human population
especially such occurrence in young children is worrisome. Management of food allergy
without side effect is still a challenge to the medical community. The objective of this study
was to investigate the effectiveness of moringa leaf extract in the treatment of food allergy
without side effects in experimental rats. Sixty (60) Wistar male rats, (4-6) weeks old,
weighing between (100-120) g were grouped into five (5) sections. They were grouped under:
Positive Control group, Negative Control group, Epinephrine control group,
Chemotherapeutic and Chemo-preventive groups. The animals were allowed to acclimatize
for two weeks where the rats were given free food ration and distilled water. After 15 days of
consecutive administration of 1 ml crude peanut extract and 10?lcholera toxin as a potent
adjuvant in rats, made food allergy established. Results from the study indicated that the
means of rectal temperatures after 20th day of allergy induction were declined from (37.17-
34.47) ?C, (37.0-34.67) ?C, and (37.52-3542) ?C in Positive control group, Chemopreventive
and Chemotherapeutic groups respectively. The reductions in rectal temperatures
confirmed that food allergy was established in experimental rats. Also the study showed that
moringa leaf extract reduced serum Immunoglobulin E levels from (324.50-275.4)ng/ml,
(181.20-170.50)ng/ml, (279.50-44.38)ng/ml respectively under Epinephrine treatment,
Chemopreventive and Chemotherapeutic experimental group treatments. This suggested
that moringa leaf extract had potential to prevent and control food allergy.

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ADEYEYE,J. . (2018). Moringa leaf extract potential in the incidence of allergy in experimental rats, 45 (), 115-115.

ADEYEYE,J. . "Moringa leaf extract potential in the incidence of allergy in experimental rats" 45, no (), (2018): 115-115.

ADEYEYE,J. and . (2018). Moringa leaf extract potential in the incidence of allergy in experimental rats, 45 (), pp115-115.

ADEYEYEJ, . Moringa leaf extract potential in the incidence of allergy in experimental rats. 2018, 45 ():115-115.

ADEYEYE,Joshua , . "Moringa leaf extract potential in the incidence of allergy in experimental rats", 45 . (2018) : 115-115.

A.Joshua , "Moringa leaf extract potential in the incidence of allergy in experimental rats" vol.45, no., pp. 115-115, 2018.

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