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Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients.

Authors: KALE Oluwafemi

Publication Type: Journal article

Journal: International Journal Of Biomedical And Health Sciences

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Abstract

Objectives: This study was designed to determine the plasma levels of some oxidative damage products
and antioxidant capacity; and investigate relationship between body mass index (BMI) and oxidative damage
parameters in three severity groups of HIV patients compared with non-HIV-infected controls. Methods: Plasma levels
of total antioxidant capacity (TAC), malondialdehyde (MDA), protein carbonyl (PCO) and advanced oxidative protein
products (AOPP) were estimated spectrophotometrically and BMI measured in controls and patients with CD4 counts
of 500 cells/?l (group1), 200-499 (group2) and <200> (p<0> comparisons of MDA, PCO and AOPP also increased significantly (p<0> (P<0> control (p<0>0.05). BMI was positively correlated with
TAC (p<0>
0.05). Conclusion: Based on the results of this study, we recommend routine BMI or weight measurement and
antioxidants supplementation in HIV subjects which is hoped to strengthen the immune system and reduce the
oxidative damage. Association of MDA with BMI was strongest followed by PCO while AOPP was least. BMI is a
reflection of oxidative damage in HIV infection.

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KALE,O. . (2011). Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients., 7 (), 1-1.

KALE,O. . "Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients." 7, no (), (2011): 1-1.

KALE,O. and . (2011). Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients., 7 (), pp1-1.

KALEO, . Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients.. 2011, 7 ():1-1.

KALE,Oluwafemi , . "Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients.", 7 . (2011) : 1-1.

K.Oluwafemi , "Oxidative damage, total antioxidant capacity and body mass index in Relation to Severity of HIV in Nigerian Patients." vol.7, no., pp. 1-1, 2011.

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