Prevalence and predictors of asymptomatic bacteriuria in HIV positive pregnant women.
Authors:
AKADRI Adebayo
Publication Type: Journal article
Journal: Online Journal Of Medicine And Medical Science Research
ISSN Number:
0
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Abstract
Asymptomatic bacteriuria constitutes a major risk factor for developing symptomatic urinary tract infection during pregnancy and may be associated with adverse effects on foetal and maternal health leading to poor pregnancy outcome. HIV infection appears to increase the prevalence of asymptomatic bacteriuria. To determine the prevalence and predictors of asymptomatic bacteriuria in HIV positive pregnant women attending antenatal clinic at the Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria. This was a cross-sectional study on 211 HIV-positive pregnant women. Information on the socio-demographic characteristics, genotype and CD4 count of the participants were recorded. Microbial culture was carried out on aseptically collected urine samples. Statistical analysis was done using IBM-SPSS Windows version 20. The prevalence of asymptomatic bacteriuria was 31.3%. Staphylococcus aureus was the most predominant organism identified accounting for 62.1% of isolates. Factors such as advanced maternal age, high socio-economic status, history of urinary tract infection in previous pregnancy and low CD4 cell count were found to have statistically significant association with asymptomatic bacteriuria. The high prevalence of asymptomatic bacteriuria among HIV-positive pregnant women justifies the need for routine screening and treatment in this obstetric population. Advanced maternal age, high socio-economic status, history of urinary tract infection in previous pregnancy and low CD4 cell count may serve as possible predictors of the condition.