Parasite-based Confirmation of Malaria with Rapid Diagnostic Tests: Challenges and Advantages
Authors:
OKANGBA Chika
Publication Type: Journal article
Journal: Scientific Journal Of Pure And Applied Sciences
ISSN Number:
0
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Abstract
The key to effective case management of malaria is prompt
and accurate diagnosis of malaria which is necessary to prevent
morbidity and mortality. Accurate and practical malaria diagnostic
such as immunochromatographic rapid diagnostic test can avert
unnecessary treatments and save lives. Malaria presents a
diagnostic challenge in most tropical countries. The urgency and
importance of obtaining results quickly from the examination of
blood samples from patient with suspected malaria is possible
with the introduction of rapid malaria diagnostic test. Rapid
diagnostic tests are useful in guiding therapeutic intervention, can
be accessible to rural and urban populations, easy to perform and
to interpret, affordable, requires no sophicated equipment and
prompt treatment of malaria. The use of rapid diagnostic test in
the case management of malaria has a lot of challenges which
includes: persistent of histidine rich protein 2 in circulation after
therapy and parasite death, effect of genetic diversity, lack of
quality control on microscopy examination, poor transportation
and storage condition, poor regulatory mechanism, lot-to-lot
variation, parasite density and lack of extensive training prior to
the use of rapid diagnostic test and supervision.