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Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria

Authors: OKANGBA Chika

Publication Type: Journal article

Journal: Scientific Journal Of Pure And Applied Sciences

ISSN Number:

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Abstract

Prompt and rapid diagnosis of malaria has gained
importance in health programmes in endemic countries, and
recognition of the importance of early, correct treatment to the
reduction in malaria morbidity and mortality. Blood-based
diagnosis using lateral-flow immunochromatographic tests,
commonly called rapid diagnostics tests (RDTs), offer great
promise in extending rapid diagnosis to areas where traditional
microscopy is not accessible. Large-scale operational use has
raised questions about the accuracy of current RDT technology in
tropical conditions. As utilization of RDTs has increased rapidly in
the last few years, there is a clear and urgent need to address
issues on quality performance and appropriateness of use,
particularly in remote endemic areas. The need for Quality
Assurance (QA) systems to maintain the quality of microscopy
diagnosis of malaria is well established but the extent of
implementation varies widely. Quality assurance process must
become an integral part of RDT budgets, procurement and
implementation plans. Responsibility for overseeing QA
processes, extending from post purchase testing of RDTs to
training and supervision of users and control of storage and
transport, should be clearly defined and coordinated from a
central level. A system of regional and referral laboratories, based
on standard operating procedures would test RDTs after purchase

and for the duration of shelf-life using quality control (QC) panels
prepared from wild-type parasites. The use of positive control
wells (PCW) containing recombinant antigens would assist in
assuring the performance of RDTs in the field and this would
assist in the parasite-base confirmation and in the case
management of malaria. Quality assurance processes must be
transparent, and good communication with manufacturers and
end-users during QA development is necessary.
© 2019 Sjournals. All rights reserved.

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OKANGBA,C. . (2019). Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria, 8 (), 858-858.

OKANGBA,C. . "Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria" 8, no (), (2019): 858-858.

OKANGBA,C. and . (2019). Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria, 8 (), pp858-858.

OKANGBAC, . Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria. 2019, 8 ():858-858.

OKANGBA,Chika , . "Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria", 8 . (2019) : 858-858.

O.Chika , "Importance of quality assurance testing of malaria rapid diagnostic test in the case management of malaria" vol.8, no., pp. 858-858, 2019.

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