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Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N

Authors: ENITAN Samson

Publication Type: Journal article

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Abstract

Introduction: Newcastle Disease is a highly contagious and commonly fatal viral poultry disease. The study was carried out to determine the efficacy of Newcastle Disease (NDV) vaccines sold at open market in Jos. Materials and methods: Five commonly used brands of ND LaSota live vaccines were used for the study. Haemagglutination test (HA) and Egg Infective Dose (EID50) was carried out on the vaccines.Sixty (60) day-old unvaccinated white leghorn broilers were distributed into 6 groups n=10 and allowed to acclimatize for 6 days. Groups 1-5 were vaccinated intraoculally with vaccines coded A - E respectively, while group 6 was not vaccinated (control group). They were bled on days 7, 14, 21 and 28 post vaccinations (PV) for antibody titration using standard methods. They were challenged. with a velogenic strain (105.5 CID50) of NDV day 35 and observed for morbidity and mortality for 14 days. Results: HA test revealed viral titres of 7log2-9log2 for vaccines with egg infectivity dose (EID50) of 107.00 to 108.49. There was progressive increase in antibody titre following vaccination. There were 100% mortalities among the control group and non in test groups. Performance of the indigenous vaccine was commendable. Conclusion: we therefore, conclude that the vaccines sold at Jos, Plateau State are potent and could prevent NDV infection and they are reliable, if standard protocols are observed. The use of the indigenous vaccine brand should also be encouraged to prevent introduction of a new strain into the country.

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ENITAN,S. . (0000). Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N, 0 (), 0-0.

ENITAN,S. . "Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N" 0, no (), (0000): 0-0.

ENITAN,S. and . (0000). Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N, 0 (), pp0-0.

ENITANS, . Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N. 0000, 0 ():0-0.

ENITAN,Samson , . "Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N", 0 . (0000) : 0-0.

E.Samson , "Evaluation of the Efficacy of Newcastle Disease (Lasota) Live Vaccines Sold in Jos, Plateau State, N" vol.0, no., pp. 0-0, 0000.

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