Viruses and cancer are often discussed separately in Nigeria’s medical circles except for Kaposi sarcoma which has been strongly associated with the human immunodeficiency virus (HIV). While the pathophysiology of the co-occurrence and co-morbidity of HIV and Kaposi sarcoma could be regarded as an indication of the need to locally expand the scope of study that links virology and oncology. This review observes the increasing level of awareness and local research interests in the co-occurrence of human papilloma virus and cervical cancer, HIV and Kaposi sarcoma; but paucity of published research works on the roles of Epstein-Barr virus in Hodgkin’s and Burkitt’s lymphoma, herpes simplex virus and cervical cancer, and cytomegalovirus and breast cancer. This review brings the underrepresentation of the roles of viruses in cancers, and vice versa, into sharp perspective with potential impacts on prevention, treatment, management and other viral and cancer disease protocols.