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Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria

Authors: ENITAN Samson

Publication Type: Journal article

Journal: International Std Research & Reviews

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Background: Herpes simplex virus type 2 (HSV-2) causes genital herpes, a chronic viral infection that is sexually transmitted and often results in genital ulcer disease (GUD) worldwide. Aim: The aim of this study was to determine the prevalence of herpes simplex virus type 2 (HSV-2) IgG and IgM antibodies and the associated risk factors among undergraduate female students of Babcock University. Methods: After ethical approval was obtained, serum samples of 150 consenting female participants (16-35 years) were collected randomly and screened using NADALR HSV-2 IgG/IgM Rapid Antibody Test Cassette (Bulgarian Company for Biotechnology, Sofia, Bulgaria). The demographic and clinical information of the participants were also collected using a structured questionnaire. The results were statistically analyzed using the SPSS version 18.0. Results: The outcome of the study shows that out of the 150 participants screened, 5 (3.3%) were positive for HSV-2 IgG antibody, 4 (2.7%) were positive for HSV-2 IgM; while 2 (1.3%) were positive for both HSV-2 IgG and IgM antibodies. There were no significant differences (P>0.05) in the seropositivity for HSV-2 IgG and IgM antibodies among the study participants on the basis of age distribution. With regards to clinical indication for genital herpes in relation to seropositivity of HSV-2 IgG and IgM antibodies among the study participants, none of the 7 (4.6%) who indicated vaginal itching was seropositive for either HSV-2 IgG or HSV-2 IgM or both. On the other hand, genital lesions were recorded in 0.7% HSV-2 IgG seropositive, 1.3% HSV-2 IgM seropositive and 0.7% HSV-2 both IgG and IgM seropositive. Genital ulcer was recorded among two participants who were either seropositive for HSV-2 IgG (0.7%) or HSV-2 IgM (0.7%). Only one (0.7%) participant indicated inguinal lymphadenopathy, however, the person was HSV-2 IgG/IgM seronegative. Identifiable risk factor significantly (P<0>

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ENITAN,S. . (2020). Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria, 9 (), 1-1.

ENITAN,S. . "Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria" 9, no (), (2020): 1-1.

ENITAN,S. and . (2020). Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria, 9 (), pp1-1.

ENITANS, . Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria. 2020, 9 ():1-1.

ENITAN,Samson , . "Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria", 9 . (2020) : 1-1.

E.Samson , "Seroprevalence of Herpes Simplex Virus Type 2 and Associated Risk Factors among Undergraduate Female Students of Babcock University, Nigeria" vol.9, no., pp. 1-1, 2020.

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