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Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria

Authors: ADEJUMO Esther , Adedeji , Omobolanle Ogundahunsi

Publication Type: Journal article

Journal: New Zealand Journal Of Medical Laboratory Science

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Abstract

Background: Lipid ratios are useful biomarkers of insulin resistance in Caucasians. This study assessed the predictive ability of triglyceride and lipid ratios in predicting insulin resistance among healthy adults in Southwest Nigeria. Methods: The study was a descriptive cross-sectional. The homeostasis model assessment for insulin resistance (HOMA- IR) was used to assess insulin resistance in healthy volunteers. The Receiver Operative Characteristics (AUC) curve was used to assess the discriminative abilities of triglyceride, the ratio of triglyceride, total cholesterol and low-density lipoprotein cholesterol (LDLc) to high-density lipoprotein cholesterol (HDLc) triglyceride/ HDLc ratio, cholesterol / HDLc ratio and LDLc / HDLc ratio respectively to discriminate insulin resistance. Results: Five hundred and twenty healthy adults were enrolled. The mean age of the participants was 46.7±14.6 years, 72.7% were females. There were no differences in mean age, total cholesterol, LDLc, triglycerides, HDLc, cholesterol/HDLc ratio, triglyceride /HDLc ratio, LDLc/HDLc ratio and HOMA-IR (p>0.05). The triglyceride /HDLc ratio had the largest AUC in men (0.591, 95% CI: 0.491 – 0.685; p= 0.122) compared to women (0.644, 95% CI: 0.586 – 0.703; p <0>

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ADEJUMO,E. Adedeji,A. Omobolanle,O. . (2020). Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria, 74 (), 83-83.

ADEJUMO,E. Adedeji,A. Omobolanle,O. . "Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria" 74, no (), (2020): 83-83.

ADEJUMO,E. and Adedeji,A. and Omobolanle,O. and . (2020). Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria, 74 (), pp83-83.

ADEJUMOE, AdedejiA, OmobolanleO, . Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria. 2020, 74 ():83-83.

ADEJUMO,Esther , Adedeji,Adejumo , and Omobolanle,Ogundahunsi . "Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria", 74 . (2020) : 83-83.

A.Esther A.Adejumo & O.Ogundahunsi , "Lipid ratios are not good predictors of insulin resistance among healthy adults from Southwest Nigeria" vol.74, no., pp. 83-83, 2020.

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