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Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria

Authors: AKINOLA Moses , OYEDELE Titus , Salami Omotayo , Kolawole Akande, Olukayode Oluyemi, Alaba Adesina, Adedeji David Adebajo

Publication Type: Journal article

Journal: Bmc Gastroenterology

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Abstract

Background: The reflux of noxious contents of the stomach may cause oesophageal and extra-oesophageal complications either by direct contact of aspirated gastric refluxate with the upper airway or by a vago-vagal reflex. This study aimed to determine the prevalence of gastroesophageal disease (GERD) and extraesophageal manifestations among undergraduate students in a tertiary institution in Nigeria. Methods: This is a cross-sectional study involving undergraduate students in a private University in Nigeria. Study proforma had three parts. Part A consisted of self-administered questionnaire designed to obtain students biodata. Part B consisted of standard Carlsson-Dent questionnaire. A score of 4 and above on Carlsson- Dent questionnaire was considered diagnostic of gastroesophageal reflux symptoms (GERD). Thereafter those who had GERD were further questioned and examined for extra-oesophageal symptoms of GERD. Results: The total number of the study participants was 647, out of which 212 (32.8%) had GERD. One hundred and forty-four (67.9%) and 86 (32.1%) females and male had GERD respectively (p = 0.13). The extraesophageal symptoms found in those with GERD were, dysphagia, coated tongue, nocturnal cough, xerostomia, lump in the throat, asthma-like symptoms, recurrent sore throat, frequent throat clearing, halithosis and dental erosion among others. Conclusion: GERD is common among this study population, with a prevalence rate of 32.8%. Only age showed significant predictor for GERD. Varying extra-oesophageal manifestations were found in those with GERD. Keywords: Gastroesophageal reflux extraesophageal disease, Nocturnal cough, Dental erosion, Halitosis

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AKINOLA,M. OYEDELE,T. Salami,O. Kolawole,O.A Olukayode,Y.O Alaba,M.A Adedeji,D.A . (2020). Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria, 20 (), 1-1.

AKINOLA,M. OYEDELE,T. Salami,O. Kolawole,O.A Olukayode,Y.O Alaba,M.A Adedeji,D.A . "Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria" 20, no (), (2020): 1-1.

AKINOLA,M. and OYEDELE,T. and Salami,O. and Kolawole,O.A and Olukayode,Y.O and Alaba,M.A and Adedeji,D.A and . (2020). Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria, 20 (), pp1-1.

AKINOLAM, OYEDELET, SalamiO, KolawoleOA, OlukayodeYO, AlabaMA, AdedejiDA, . Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria. 2020, 20 ():1-1.

AKINOLA,Moses , OYEDELE,Titus , Salami,Omotayo , Kolawole,Oluseyi Akande, Olukayode,Yinka Oluyemi, Alaba,Moses Adesina, and Adedeji,David Adebajo . "Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria", 20 . (2020) : 1-1.

A.Moses O.Titus S.Omotayo K.Oluseyi Akande O.Yinka Oluyemi A.Moses Adesina & A.David Adebajo , "Gastroesophageal reflux disease: prevalence and Extraesophageal manifestations among undergraduate students in South West Nigeria" vol.20, no., pp. 1-1, 2020.

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