Iron Studies in Busulfan Induced Aplasia Using New Zealand White Rabbits Fed with Hypoproteic Diet
Authors:
ENITAN Samson
Publication Type: Journal article
Journal: Sokoto Journal Of Medical Laboratory Science
ISSN Number:
0
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Abstract
There is paucity of literature on iron levels during cancer chemotherapy using busulfan. The relationship between dietary protein iron levels and haemoglobin formation during marrow suppression is not well documented. Iron parameters were studied in New Zealand White rabbits induced with aplastic anaemia and maintained on hypoproteic or protein rich diet. The animals were fed on diet containing 30% protein for four weeks and grouped into four (A-D) groups of five rabbits each. Group A and C animals had their feed substituted to a hypoproteic diet (< 4>0.05). The mean levels of serum iron, UIBC, TIBC, haemoglobin and ferritin of animals in group C were significant when compared with those of animals in group D (p<0>