Journal: Journal Of Clinical Case Reports And Trials
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Abstract
Traumatic brain injury (TBI) remains a significant disease burden with great impact on the patient, his family and the community. White blood cell (WBC) count is a laboratory test routinely done in trauma care and has been shown to be predictive of outcome in TBI but the strength of prediction has not been known in comparison with other outcome parameters such as Glasgow coma scale-extended (GOS-E). This research was aimed at comparing the predictive strength of the total white blood cell count within 24 hours of TBI with outcome using GOS-E. This was a one-year prospective hospital-based study of all patients that presented at the Lagos University Teaching Hospital (LUTH) over a year period with clinical and radiological evidence of TBI within 24 hours of injury and the GOS-E was assessed at six (6) month post injury. One hundred and fifty-eight patients with traumatic brain injury who met the inclusion criteria were studied of the 199 patients recruited. 73.4% of these patients were male and 26.6% were female with a male to female ratio of 3.6:1. A negative correlation was shown between GOS-E done at 6 months post-TBI with total WBC count within 24 hours post-TBI at a correlation coefficient of - 0.090. This study concluded that total white blood cell count done within 24 post-injury is a weak predictor of outcome in patients with TBI compared to GOS-E.