Antiulcer and Blood-Boosting Activities of Feeds Supplemented with Trametes Versicolor from Nigeria
Authors:
AINA Ayandiran
Publication Type: Journal article
Journal: Scholars Academic Journal Of Biosciences
ISSN Number:
0
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Abstract
ntiulcer and blood-boosting activities of feeds supplemented with Trametes versicolar (Tv) in Wistar rats (Rattus norvegicus) were studied. Haematological studies and antiulcer biochemical analysis were carried out on the rats using standard methods.Data were presented as Mean ± SEM, analyzed using two-way ANOVA and p ? 0.05 was significantly different in all the variables.Haematological parameterswere not significantly different across all Tv treatments when compared with the control (CN).There were alsosignificant differences invalues obtained forgastric ulcer inhibition, nitric oxide, mucin, sulfhydryl, and H+/K+-ATPase.Tvtreatment groups also differed when compared with ulcerated untreated control(CU). The pathological changes detected from histological studies on the stomach tissues showed inhibition of ulcers. Tv treatment groups demonstrated blood boosting andantiulcer activity through synergistic activities of mucin, H+/K+ATPase activity, and antioxidant mechanism.The implications of these observations are discussed.