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Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease

Authors: MORGAN Eghosa

Publication Type: Journal article

Journal: Roman Journal Of Neurosurgery

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Abstract

This review highlights the microbiota gut-brain axis and neurodegenerative diseases
excluding studies on animal models. Gut microbiota is capable of modulating some
brain activities via the microbiota gut-brain axis. A bidirectional communication exists
between the gastrointestinal (GI) tract and the central nervous system (CNS) in the
microbiota gut-brain axis. Gut dysbiosis has been linked to neurodegenerative
diseases as a result of the imbalance in the composition of its microbiota, which has
a damaging effect on the host’s health. The association between the role and
mechanism of CNS disease and gut microbial is yet to be fully explored. Although
some studies have shown a positive relationship between a rich diverse microbial
community and the brain of the host, and a negative relationship between microbial
dysbiosis, intestinal infection and human brain health, our knowledge, however, is
limited due to the inability to identify the major players in this heterogeneous
microbial community.

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MORGAN,E. . (2020). Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease, 1 (), 116-116.

MORGAN,E. . "Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease" 1, no (), (2020): 116-116.

MORGAN,E. and . (2020). Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease, 1 (), pp116-116.

MORGANE, . Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease. 2020, 1 ():116-116.

MORGAN,Eghosa , . "Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease", 1 . (2020) : 116-116.

M.Eghosa , "Microbiota Gut-Brain Axis and Neurodegenerative Disease. A systematic review on Alzheimer’s disease, Amyotrophic lateral sclerosis and Parkinson Disease" vol.1, no., pp. 116-116, 2020.

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