GREEN SYNTHESIS OF SILVER NANOPARTICLES, CHARACTERIZATION AND BIOMEDICAL APPLICATIONS: A REVIEW
Authors:
AMODU Samuel
Publication Type: Journal article
Journal: ABUAD INTERNATIONAL JOURNAL OF NATURAL AND APPLIED SCIENCES
ISSN Number:
0
Downloads
1
Views
Abstract
The ongoing rise in antimicrobial resistance is one of the urgent challenges in international public health thereby undermining the effectiveness of conventional antimicrobials. Silver nanoparticles, synthesized through environmentally friendly plant-mediated methods, offer a promising opportunity because of sustainability and price-effectiveness. The utilization of reducing agents inclusive of flavonoids, phenolics, terpenoids and different phytochemicals aid the reduction of Ag+ ions and stabilize nanoparticles. This evaluation gives a comprehensive look on plant-based synthesis of silver nanoparticles and key elements which include pH, temperature, and extract-to-metallic ion ratio which has an impact on nanoparticle size, morphology, and stability that affect nanoparticle synthesis. Some characterization techniques which include UV-Vis spectroscopy, Fourier-transform infrared spectroscopy, X-ray diffraction, Dynamic light scattering, and both scanning and transmission electron microscopy are discussed in relation to features. Plant-derived silver nanoparticles showcase effective antimicrobial mechanisms that aid cell membranes disruption, oxidative pressure, biofilm inhibition, and gene expression modulation. Plant-derived silver nanoparticles have shown capability in wound healing, centered drug transport, anticancer cures, and biosensing. However, cytotoxicity, insufficient biocompatibility records, and the absence of standardized synthesis protocols avert clinical development. Further research must prioritize system optimization, precise analysis of in vivo conduct, and integration into multifunctional clinical structures to absolutely harness silver nanoparticles’ ability in fighting antimicrobial resistance and using innovations in modern medicine.