Lazarus Osekete was born in 1915 and died in 2010. Osekete was the first Seventh-day Adventist member and clergy from Obiaruku town in Ukuani Kingdom of Delta State. Osekete was married to Lydia Osekete (nee Aswa). He was a selfless, true representation of his faith and a devoted evangelist and mentor. This biography is intended to address the African culture and missiological historiography based on the dearth of materials on Africaness and historio- missiological accounts which this paper met. It examines the level of sacrifice, cultural issues and the best devotion to employ by African missionaries. The paper employed the descriptive methodology as it gathered sources from the primary, secondary and archival material in this study. This paper concluded that if studied, it will serve as a practical tool for historical and missiological studies in a typical African milieu.