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Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets

Authors: ONIGBINDE ADEBAYO

Publication Type: Journal article

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Abstract

Doxepin is tricyclic antidepressant derivative of phenylamine. Tricyclic antidepressant have a symparthicolyic , which occur few days after treatment. The desired antidepressant effect occur 2 t0 3 weeks. Figure 1 shows overlaid chromatogram of doxepin standard and the extracts from Aponal 100 tablets. The autosampler was set at 4 degree centigrade to avoid decomposition of the samples. The analysis was done on an Eclipse XDB-C18 column, and extra densely packed C-18 column made with special Zorbax silica support designed to reduce or eliminate strong adsorption basic or acid compounds

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ONIGBINDE,A. . (0000). Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets, 0 (), 0-0.

ONIGBINDE,A. . "Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets" 0, no (), (0000): 0-0.

ONIGBINDE,A. and . (0000). Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets, 0 (), pp0-0.

ONIGBINDEA, . Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets. 0000, 0 ():0-0.

ONIGBINDE,ADEBAYO , . "Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets", 0 . (0000) : 0-0.

O.ADEBAYO , "Tricyclic Antidepressant: HPLC Anslysis of Doxepin in 'Aponal 100' Tablets" vol.0, no., pp. 0-0, 0000.

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