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Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L.

Authors: EDWARD BABATUNDE ESAN

Publication Type: Journal article

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Abstract

ABSTRACT Objective: Garden croton, Codiaeum variegatum (L.) Blume, a beautifully variegated leafy perennial, tropical ornamental herb with glabrous branches and prominent leafy scar has generated a lot of scientific enquiry. However, there is paucity of information on its toxicity. This study investigated the effects of aqueous and alcoholic leaf extracts of C. variegatum on blood clotting and coagulation time, as well as the antimicrobial and phytochemical profile of its bioactive constituents. Results: The leaf methanolic extract tested positive for alkaloid, anthraquinone, cardiac glycosides, saponins, phlobatanins, tannins, cardenolids, steroids, flavonoids, phenols and phyllates. The ethanolic extract of leaf inhibited growth of Streptococcus pneumoniae Te2 (30 mm), S. pyrogeneae Td2 (14 mm), Salmonella typhi Tc2 (7 mm), S. typhi Tc19 (13 mm), S. typhi Sat7 (10 mm) and Escherichia coli Ecl7 (17 mm).

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,E. . (0000). Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L., 0 (), 0-0.

,E. . "Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L." 0, no (), (0000): 0-0.

,E. and . (0000). Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L., 0 (), pp0-0.

E, . Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L.. 0000, 0 ():0-0.

,EDWARD BABATUNDE ESAN , . "Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L.", 0 . (0000) : 0-0.

.EDWARD BABATUNDE ESAN , "Biochemical and antimicrobial effects of aqueous and alcoholic extracts of Codiaeum variegatum (L." vol.0, no., pp. 0-0, 0000.

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